Infertility - Liver Depression Pattern

TCM differentiation and treatment for infertility with

Infertility · Liver Depression Pattern

Updated: June 23, 2026

Reviewed by: Dr. Li Wei, DACM

Reading Time: 7 min

Body Area: Pelvis


Pattern Overview

Liver Depression is a common pattern in infertility, characterized by

**psychological factors causing ovulation disorders, elevated prolactin,

tubal spasm, endometriosis, and emotional symptoms**. The core

pathogenesis is chronic stress causing Liver-Qi stagnation, leading

to endocrine dysfunction, tubal spasm, and impaired fertility.


Key Symptoms and Differentiation Points

Differentiation Dimension Manifestations
Primary Symptoms

premenstrual tension, emotional instability |

Associated Symptoms

irritability, depression, abdominal pain |

Tongue and Pulse

pulse |

Pathogenesis

and tubal spasm |

Etiology

factors, anxiety |


Acupuncture Point Prescription

Point Location Function
Ganshu (BL18) Lower back, 1.5 cun lateral to T9

of Liver meridian; soothes Liver-Qi |

Taichong (LR3)

metatarsals | Source point of Liver meridian; soothes Liver-Qi |

Sanyinjiao (SP6) 3 cun above the medial malleolus

menstruation and harmonizes Liver and Spleen |

Qimen (LR14)

the nipple | Front-Mu point of Liver meridian; regulates Liver-Qi |

Neiguan (PC6)
Relieves chest tightness and calms the spirit

Clinical Recommendation: Filament needle, reducing method; combine

with stress reduction techniques and counseling.


Herbal Formula

Base Formula: Kai Yu Zhong Yu Tang (开郁种玉汤) or Bai Ling Diao Gan

Tang (百灵调肝汤)

Composition:

White Peony (Bai Shao), Cyperus (Xiang Fu), Angelica (Dang Gui),

Atractylodes (Bai Zhu), Moutan (Dan Pi), Poria (Fu Ling), Trichosanthes

Root (Tian Hua Fen)

Action: Soothes Liver-Qi, regulates menstruation, and promotes

conception.

Modifications

Associated Symptoms Additions/Subtractions
Elevated prolactin Add Xia Ku Cao, Mai Ya to regulate prolactin
Tubal spasm Add Bai Shao, Gan Cao to relax muscles
Endometriosis Add Tao Ren, Hong Hua to invigorate blood
Insomnia Add Suan Zao Ren, Yuan Zhi to calm the spirit

Western Mechanism Reference

Psychological factors causing ovulation disorders, elevated prolactin,

tubal spasm, and endometriosis-related infertility. Liver Depression

corresponds to infertility associated with stress, where psychological

factors contribute to endocrine dysfunction, tubal spasm, and impaired

fertility.


References

1. Gynecology of TCM - Infertility with Liver Depression.

2. Zang-Fu Pattern Differentiation: Liver-Qi Stagnation → Pivot Layer.

3. WHO. (2023). Infertility fact sheet. World Health Organization.


Explore More

Personalized herbal protocols and acupressure tools for women's health.

research papers and clinical case studies on TCM infertility management.


Last reviewed: June 2026 | Lead author: Dr. Li Wei, DACM | Content updated: Monthly

Disclaimer: This guide is for educational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any treatment.