Alopecia Areata - Liver-Kidney Deficiency Pattern

TCM differentiation and treatment for alopecia areata with

Alopecia Areata · Liver-Kidney Deficiency Pattern

Updated: June 23, 2026

Reviewed by: Dr. Li Wei, DACM

Reading Time: 7 min

Body Area: Skin


Pattern Overview

Liver-Kidney Deficiency is a chronic pattern in alopecia areata,

characterized by **hair follicle stem cell dysfunction, Wnt/β-catenin

signaling abnormality, hair follicle papilla cell apoptosis, and chronic

hair loss. The core pathogenesis is Liver-Kidney deficiency failing

to nourish the hair follicles**, leading to stem cell dysfunction and

impaired hair growth.


Key Symptoms and Differentiation Points

Differentiation Dimension Manifestations
Primary Symptoms

regrowth, weak hair |

Associated Symptoms

dizziness, tinnitus, fatigue |

Tongue and Pulse

and weak pulse |

Pathogenesis

follicles |

Etiology

deficiency |


Acupuncture Point Prescription

Point Location Function
Ganshu (BL18) Lower back, 1.5 cun lateral to T9

of Liver meridian; nourishes Liver-Blood |

Shenshu (BL23) Lower back, 1.5 cun lateral to L2

point of Kidney meridian; tonifies Kidney-Essence |

Taixi (KI3)

tendon | Source point of Kidney meridian; nourishes Kidney-Yin |

Sanyinjiao (SP6) 3 cun above the medial malleolus

Blood and Yin; regulates the Spleen and Kidney |

Baihui (GV20)

anterior hairline | Lifts Qi and promotes hair growth |

Clinical Recommendation: Filament needle, reinforcing method;

moxibustion may be applied to Shenshu and Ganshu to warm and tonify.


Herbal Formula

Base Formula: Qi Bao Mei Ran Dan (七宝美髯丹)

Composition:

Polygonum (He Shou Wu), Poria (Fu Ling), Achyranthes (Niu Xi), Angelica

(Dang Gui), Goji Berry (Gou Qi), Cuscuta (Tu Si Zi), Psoralea (Bu Gu

Zhi), Licorice (Gan Cao)

Action: Tonifies Liver and Kidney, nourishes Essence, and promotes

hair growth.

Modifications

Associated Symptoms Additions/Subtractions
Chronic hair loss Add Gou Qi, Tu Si Zi to nourish Kidney-Essence
Lower back and knee soreness

lower back |

Fatigue Add Huang Qi to enhance Qi supplementation
Dizziness

eyes |


Western Mechanism Reference

Hair follicle stem cell dysfunction with Wnt/β-catenin signaling

abnormality, and hair follicle papilla cell apoptosis. Liver-Kidney

Deficiency corresponds to chronic alopecia areata with hair follicle

stem cell dysfunction, where Wnt/β-catenin signaling abnormalities and

papilla cell apoptosis contribute to impaired hair growth.


References

1. Dermatology of TCM - Alopecia Areata with Liver-Kidney Deficiency.

2. Zang-Fu Pattern Differentiation: Liver-Kidney Yin Deficiency →

Cross-layer.

3. WHO. (2023). Skin health. World Health Organization.


Explore More

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research papers and clinical case studies on TCM dermatology.


Last reviewed: June 2026 | Lead author: Dr. Li Wei, DACM | Content updated: Monthly

Disclaimer: This guide is for educational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any treatment.