Irritable Bowel Syndrome - Liver Depression with Spleen

TCM differentiation and treatment for irritable bowel

Irritable Bowel Syndrome · Liver Depression with Spleen Deficiency

Pattern

Updated: June 23, 2026

Reviewed by: Dr. Li Wei, DACM

Reading Time: 7 min

Body Area: Abdomen


Pattern Overview

Liver Depression with Spleen Deficiency is the most common pattern in

irritable bowel syndrome (IBS), characterized by **gut-brain axis

dysregulation, abdominal pain triggered by stress, alternating diarrhea

and constipation, and bloating. The core pathogenesis is emotional

stress causing Liver Qi depression**, which overacts on the Spleen,

leading to visceral hypersensitivity and abnormal gut motility.


Key Symptoms and Differentiation Points

Differentiation Dimension Manifestations
Primary Symptoms

alternating diarrhea/constipation |

Associated Symptoms

tightness, poor appetite |

Tongue and Pulse

pulse |

Pathogenesis

Qi dysfunction |

Etiology

habits |


Acupuncture Point Prescription

Point Location Function
Taichong (LR3)

metatarsals | Source point of Liver meridian; soothes Liver Qi |

Tianshu (ST25) 2 cun lateral to the umbilicus

of Large Intestine; regulates bowel function |

Zusanli (ST36)

to the tibial crest | Strengthens Spleen and Stomach; tonifies Qi |

Pishu (BL20) Lower back, 1.5 cun lateral to T11

of Spleen meridian; strengthens Spleen Qi |

Sanyinjiao (SP6) 3 cun above the medial malleolus

and Blood; harmonizes Liver and Spleen |

Clinical Recommendation: Filiform needle, reducing method for Liver

points, reinforcing method for Spleen points; combine with stress

reduction techniques.


Herbal Formula

Base Formula: Chai Shao Liu Jun Zi Tang (柴芍六君子汤) + Tong Xie

Yao Fang (痛泻要方)

Composition:

Bupleurum (Chai Hu), White Peony (Bai Shao), Ginseng (Ren Shen),

Atractylodes (Bai Zhu), Poria (Fu Ling), Tangerine Peel (Chen Pi),

Saposhnikovia (Fang Feng), Licorice (Gan Cao)

Action: Soothes Liver Qi, strengthens Spleen Qi, stops diarrhea, and

relieves pain.

Modifications

Associated Symptoms Additions/Subtractions
Severe abdominal pain

and stop pain |

Diarrhea-predominant

and stop diarrhea |

Constipation-predominant

promote bowel movement |

Bloating

|


Western Mechanism Reference

Gut-brain axis dysregulation causing visceral hypersensitivity, abnormal

gut motility, and CRH-induced intestinal movement. Liver Depression with

Spleen Deficiency corresponds to IBS associated with stress, where HPA

axis activation and CRH release contribute to visceral hypersensitivity

and abnormal gut motility.


References

1. Internal Medicine of TCM - Diarrhea with Liver Overacting on Spleen.

2. DB-XJB: Chai Shao Liu Jun Zi Tang.

3. Lembo, A., et al. (2016). Acupuncture for IBS. *American Journal of

Gastroenterology*, 111(8), 1145-1153.

4. WHO. (2023). Digestive health. World Health Organization.


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Last reviewed: June 2026 | Lead author: Dr. Li Wei, DACM | Content updated: Monthly

Disclaimer: This guide is for educational purposes only and does not constitute medical advice. Consult a licensed healthcare provider before starting any treatment.